CBDV Effects: Learn the Wonders CBDV Can Do to the Body
Medical cannabis has been used by ancient physicians in many parts of the world as medicine to treat
pain and other ailments. In the 19th century, cannabis was introduced for therapeutic use in Western Medicine, and the rest is history. The more known cannabinoid offering health benefits is CBD, but have you heard of CBDV? If you haven’t yet, we’re about to tell you about CBDV and its therapeutic effects on the human body.
Firstly, What is CBDV?
CBDV, short for Cannabidivarin is a non-psychoactive cannabinoid, which means it will not cause the euphoric feeling of being “high.” This cannabinoid is found more prevalent in indica strains, specifically landrace indica strains, and strains that are lower in tetrahydrocannabinol (THC).
In terms of chemical structure, CBDV is closely related to CBD, which both have 30 stereoisomers, and seven double bond isomers. Hence, CBDV can be referred to as CBD’s cousin.
Strains with high CBDV content include indicas like Medical Mass Euphoria and sativas like Painkiler XL, Royal Medic, and Dance World.
What is CBDV
How Does CBDV Work?
It is best to review that our bodies have an endocannabinoid (EC) system. The EC system is a communication system that sends messages throughout our brains and bodies. The body naturally produces cannabinoids that interact with receptors in the EC system to regulate functions such as sleep, bone growth, blood pressure, and so much more.
Humans have cannabinoid receptors on most parts of the brain, the immune system, and other organs. Cannabinoids from marijuana can bind to these receptors like the natural cannabinoids produced by our bodies and create responses we usually regulate with our EC system.
Many of the cannabinoid receptors in the parts of the brain that controls coordination, memory, movement, judgment, and pleasure. Cannabinoids from the marijuana plant might affect the following parts of the brain:
Hypothalamus: Affects hunger and sexual behavior
Basal ganglia: Involves motor control
Ventral striatum: Involves feelings of reward
Amygdala: Controls fear, emotion, and anxiety
Brain stem and spinal cord: Involves feelings of pain and the urge to vomit
Neocortex: Incorporates sensory information and involves higher cognitive functions
Hippocampus: Involves memory and learning
Cerebellum: Involves motor control and coordination
THC attaches to cannabinoid receptors and creates a “high” feeling. Non-psychoactive cannabinoids like CBD and CBDV encourage the body to use more of its natural cannabinoids and do not make the user feel high.
The Potential Medical Benefits of CBDV
Although less researched compared to its cousin CBD, CDBV shows potential healing properties. Much of the research around CBDV has centered around its effect on seizures. GW Pharmaceuticals, which developed the first FDA-approved CBD medicine for epilepsy called Epidiolex. They are also actively developing a CBDV-based drug known as GPW42006 to reduce or prevent epileptic and other forms of seizures.
Their research has shown that CBDV affects the neurochemical pathway of the capsaicin receptors involved in both the onset and the progression of several types of epilepsy. GW reports that CBDV has shown anti-epileptic results “across a range of in vitro and in vivo models of epilepsy.”
CBDV is also showing promise in other therapeutic potential:
- The research done by GW Pharmaceuticals showed that CBDV affects the neurochemical pathway of the capsaicin receptors involved in both the onset and the progression of several types of epilepsy. In addition, GW reported that CBDV has shown anti-epileptic results “across a range of in vitro and in vivo models of epilepsy.”
- According to a 2019 CBDV rodent study published in National Center for Biotechnology Information Journal, it has shown promise in helping the neurobehavioral issues associated with Rett syndrome. Rett syndrome is caused by an X chromosome mutation that affects girls with seizures, speech issues, and muscle spasticity. CBDV seems to help with both the genetically determined and chemically-induced forms of this and similar diseases.
- In a 2019 study published in the British Journal of Pharmacology, CBDV showed potential for patients struggling with Duchenne Muscular Dystrophy (DMD). This muscle disease is characterized by chronic inflammation and irreversible skeletal muscle damage and degeneration. CBDV can potentially reduce inflammation and restore and even enhance muscle function. CBDV is also shown to improve locomotion, highlighting the compound’s potential as a new therapy for DMD.
- A rodent CBDV study published in 2013 showed that the cannabinoid may also be a powerful anti-nausea agent. Initial research on rodents shows that CBDV likely acts as an agonist to the CB1 receptors, thereby blocking the nausea response.
Although CBDV was discovered 50 years ago, research is just in its infancy. With GW Pharmaceuticals and their CBDV clinical trials underway, this is a hopeful beginning in unlocking the secrets of this potentially powerful cannabinoid.
CBDV Benefits According to Science
Does CBDV Have Any Side Effects?
As of this writing, CBDV hasn’t been shown to produce any adverse effects. However, that doesn’t mean it is necessarily devoid of any adverse outcomes. We simply need more research to determine this cannabinoid’s safety profile.
How Is CBDV Taken?
CBDV, like CBD, is extracted from the marijuana or hemp plant. In its extracted form, it can be administered in the same way as any medical marijuana product. Popular methods for non-psychoactive cannabinoid consumption can include:
Tinctures: Tinctures are a liquid form mostly made of raw hemp oil containing the cannabinoids. It’s the easiest method of administration. All you need to do with a tincture is place a few drops under your tongue when needed. You can also add tinctures to food and drinks. If you take the tincture under the tongue, it will reach your bloodstream faster than if you consume it in food.
Gel capsules: Gel capsules are the same as tinctures, but are packaged in a dissolvable shell. Some patients prefer capsules because they look more like traditional pills and because each capsule contains a specific dose.
Dabbing: Dabbing involves inhaling the vapors from a concentrated form of CBDV or CBD. Cannabis dabs are typically inhaled after they’re heated.
Vaping: Vaping cannabinoids involves inhaling heated oil forms of the substance. Vaping might be a great option for someone who is looking to replace nicotine vaping with something healing and non-addictive.
Topical lotions: Topical applications may work faster than other forms, but typically don’t last as long. Many patients choose topical forms in combination with other methods for long-lasting effects. Topical use is ideal for people who suffer from aches and pains associated with arthritis, fibromyalgia and other disorders.
Cannabis connoisseurs can also consume it as vapor, In food or beverages, and applying medical marijuana lotions. Topical application is the healthiest form of medical marijuana consumption, while smoking the medicine is the least recommended.
CBDV Effects: In Summary
Just like any other cannabinoid, CBDV interacts with the endocannabinoid system, which in turn offers amazing effects to the body. Just like its cousin, CBDV does not offer psychoactive effects, which don’t make you high.
Albeit less popular than other cannabinoids, CDBV shows potential benefits and effects in the medical marijuana industry. This non-intoxicating cannabinoid can be a gamechanger for people with epilepsy, Rhett syndrome, Duchenne muscular dystrophy, and nausea.
If you’re one of the people with the abovementioned conditions, remember to consult your doctor or healthcare provider first before taking any cannabis supplement.
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